On Epstein's trajectory model of non-relativistic quantum mechanics

In 1952 Bohm presented a theory about non-relativistic point-particles moving along deterministic trajectories and showed how it reproduces the predictions of standard quantum theory. This theory was actually presented before by de Broglie in 1926, but Bohm's particular formulation of the theory inspired Epstein to come up with a different trajectory model. The aim of this paper is to examine the empirical predictions of this model. It is found that the trajectories in this model are in general very different from those in the de Broglie-Bohm theory. In certain cases they even seem bizarre and rather unphysical. Nevertheless, it is argued that the model seems to reproduce the predictions of standard quantum theory (just as the de Broglie-Bohm theory).Comment: 12 pages, no figures, LaTex; v2 minor improvement

ON COMPUTER SIMULATION AS A COMPONENT IN INFORMATION SYSTEMS RESEARCH

Computer simulation is widely regarded as a useful activity during various phases of research. However, depending on its context, the meaning, definition, and focus of the term can vary: In traffic planning, for example, simulation is used to determine useful configurations of a road network, thus focusing on the environment. An entirely different perspective is used within multi-agent systems. In such settings, the environment of the agents remains static, while the interesting research questions concern the behavior of the agents themselves. The research focuses on the microscopic level and the resulting emergent behavior. This article puts such diverse meanings in the context of a research process that treats descriptive and prescriptive research as two sides of the same coin. We develop a framework to classify different types of simulation, based on the actual research activity they are intended to be used for. Two case studies supplement the framework

Dynamic Scaling and Two-Dimensional High-Tc Superconductors

There has been ongoing debate over the critical behavior of two-dimensional superconductors; in particular for high Tc superconductors. The conventional view is that a Kosterlitz-Thouless-Berezinskii transition occurs as long as finite size effects do not obscure the transition. However, there have been recent suggestions that a different transition actually occurs which incorporates aspects of both the dynamic scaling theory of Fisher, Fisher, and Huse and the Kosterlitz-Thouless-Berezinskii transition. Of general interest is that this modified transition apparently has a universal dynamic critical exponent. Some have countered that this apparent universal behavior is rooted in a newly proposed finite-size scaling theory; one that also incorporates scaling and conventional two-dimensional theory. To investigate these issues we study DC voltage versus current data of a 12 angstrom thick YBCO film. We find that the newly proposed scaling theories have intrinsic flexibility that is relevant to the analysis of the experiments. In particular, the data scale according to the modified transition for arbitrarily defined critical temperatures between 0 K and 19.5 K, and the temperature range of a successful scaling collapse is related directly to the sensitivity of the measurement. This implies that the apparent universal exponent is due to the intrinsic flexibility rather than some real physical property. To address this intrinsic flexibility, we propose a criterion which would give conclusive evidence for phase transitions in two-dimensional superconductors. We conclude by reviewing results to see if our criterion is satisfied.Comment: 14 page

Nuclear Octupole Correlations and the Enhancement of Atomic Time-Reversal Violation

We examine the time-reversal-violating nuclear ``Schiff moment'' that induces electric dipole moments in atoms. After presenting a self-contained derivation of the form of the Schiff operator, we show that the distribution of Schiff strength, an important ingredient in the ground-state Schiff moment, is very different from the electric-dipole-strength distribution, with the Schiff moment receiving no strength from the giant dipole resonance in the Goldhaber-Teller model. We then present shell-model calculations in light nuclei that confirm the negligible role of the dipole resonance and show the Schiff strength to be strongly correlated with low-lying octupole strength. Next, we turn to heavy nuclei, examining recent arguments for the strong enhancement of Schiff moments in octupole-deformed nuclei over that of 199Hg, for example. We concur that there is a significant enhancement while pointing to effects neglected in previous work (both in the octupole-deformed nuclides and 199Hg) that may reduce it somewhat, and emphasizing the need for microscopic calculations to resolve the issue. Finally, we show that static octupole deformation is not essential for the development of collective Schiff moments; nuclei with strong octupole vibrations have them as well, and some could be exploited by experiment.Comment: 25 pages, 4 figures embedded in tex

Understanding Business Process Quality

Abstract Organizations have taken benefit from quality management prac-tices in manufacturing and logistics with respect to competitiveness as well as profitability. At the same time, an ever-growing share of the organizational value chain centers around transactional administrative processes addressed by business process management concepts, e.g. in finance and accounting. Integrating these fields is thus very promising from a management perspec-tive. Obtaining a clear understanding of business process quality constitutes the most important prerequisite in this respect. However, related approaches have not yet provided an effective solution to this issue. In this chapter, we consider effectiveness requirements towards business process quality concepts from a management perspective, compare existing approaches from various fields, deduct a definition framework from organizational targets, and take initial steps towards practical adoption. These steps provide fundamental in-sights into business process quality, and contribute to obtain a clear grasp of what constitutes a good business process.

Epstein-Barr virus: clinical and epidemiological revisits and genetic basis of oncogenesis

Epstein-Barr virus (EBV) is classified as a member in the order herpesvirales, family herpesviridae, subfamily gammaherpesvirinae and the genus lymphocytovirus. The virus is an exclusively human pathogen and thus also termed as human herpesvirus 4 (HHV4). It was the first oncogenic virus recognized and has been incriminated in the causation of tumors of both lymphatic and epithelial nature. It was reported in some previous studies that 95% of the population worldwide are serologically positive to the virus. Clinically, EBV primary infection is almost silent, persisting as a life-long asymptomatic latent infection in B cells although it may be responsible for a transient clinical syndrome called infectious mononucleosis. Following reactivation of the virus from latency due to immunocompromised status, EBV was found to be associated with several tumors. EBV linked to oncogenesis as detected in lymphoid tumors such as Burkitt's lymphoma (BL), Hodgkin's disease (HD), post-transplant lymphoproliferative disorders (PTLD) and T-cell lymphomas (e.g. Peripheral T-cell lymphomas; PTCL and Anaplastic large cell lymphomas; ALCL). It is also linked to epithelial tumors such as nasopharyngeal carcinoma (NPC), gastric carcinomas and oral hairy leukoplakia (OHL). In vitro, EBV many studies have demonstrated its ability to transform B cells into lymphoblastoid cell lines (LCLs). Despite these malignancies showing different clinical and epidemiological patterns when studied, genetic studies have suggested that these EBV- associated transformations were characterized generally by low level of virus gene expression with only the latent virus proteins (LVPs) upregulated in both tumors and LCLs. In this review, we summarize some clinical and epidemiological features of EBV- associated tumors. We also discuss how EBV latent genes may lead to oncogenesis in the different clinical malignancie

History of clinical transplantation

How transplantation came to be a clinical discipline can be pieced together by perusing two volumes of reminiscences collected by Paul I. Terasaki in 1991-1992 from many of the persons who were directly involved. One volume was devoted to the discovery of the major histocompatibility complex (MHC), with particular reference to the human leukocyte antigens (HLAs) that are widely used today for tissue matching.1 The other focused on milestones in the development of clinical transplantation.2 All the contributions described in both volumes can be traced back in one way or other to the demonstration in the mid-1940s by Peter Brian Medawar that the rejection of allografts is an immunological phenomenon.3,4 © 2008 Springer New York

Blocking FSH induces thermogenic adipose tissue and reduces body fat

Functional Genomics of Systemic Disorder